Formulation And Physical Evaluation Of Cream Preparations Collagen With Concentration Variations Trietanolamine As an Emulgator

Abstract

Indonesia is a country that has a climate with an average temperature above 18ᴼC, thus allowing the skin of the Indonesian people to be exposed to sunlight more often. Skin that is often exposed to sunlight causes skin condition to darken and causes a number of skin injuries. To improve the layer structure of the skin, collagen is needed. Collagen is a type of structural protein composed of several amino acids. Collagen is a protein that can be found in skin, tendons, cartilage, and organs by contributing about 30% or more of the total protein. The research method used was an experimental method by making collagen cream preparations with varying concentrations of triethanolamine as an emulsifier of 2%, 3% and 4%. Testing the physical properties of the cream includes testing organoleptic, homogeneity, pH, type of cream, spreadability, adhesion, viscosity, irritation, and hedonic. The results of the physical evaluation of the cream on the three formulas, namely F1, F2, and F3 respectively, namely the spreadability test F1 5.72 ± 0.36; F2 6.08 ± 0.35 and F3 7.16 ± 0.58. F1 adhesion test 8.38 ± 0.27; F2 6.78 ± 0.31 and F3 5.76 ± 0.61. F1 Viscosity Test 3927.52 ± 17.07; F2 3912.76 ± 0.36 and F3 3854.96 ± 42.88. The results of a good physical evaluation of collagen cream in the hedonic test were obtained in formula 3 which was the most preferred by the panelists. Based on the results of the One Way ANOVA and Kruskal-Wallis tests, it can be concluded that variations in the concentration ofm triethanolamine emulsifier have a significant effect on physical evaluation which includes pH, adhesion, spreadability, viscosity, and hedonic tests.